Any of a number of illnesses or conditions that are the direct result of the mutation of one or more genes. Some genetic disorders are hereditary, transmitted from parent to offspring, but others occur spontaneously and are not familial in origin.
An inherited congenital bleeding disorder that is caused by a deficiency of coagulation factor VIII, a protein that affects platelet function. The bleeding tendency manifests at an early age and is characterized by nose bleeds, easy bruising and, rarely, the appearance of small, purplish hemorrhagic spots on the skin. Bleeding in the intestinal tract during surgery and excess loss of blood during menstruation are common. The symptoms decrease in severity with age and during pregnancy. The disease is equally prevalent in men and women.
The above terms and definitions are part of the Taxonomy of Human Services, used here by permission of INFO LINE of Los Angeles.